DNA METHYLATION PATTERNS OF CIRCADIAN AND ULTRADIAN GENES ARE ALTERED IN THE PERIPHERAL BLOOD OF PATIENTS WITH HIDRADENITIS SUPPURATIVA

DNA methylation patterns of circadian and ultradian genes are altered in the peripheral blood of patients with hidradenitis suppurativa

BackgroundHidradenitis suppurativa (HS) is a chronic inflammatory skin condition that affects hair follicles in areas with apocrine sweat glands, such as the underarms, groin, and buttocks.The pathogenesis of HS is not fully understood, but considering the key role played by the biological clock in the control of immune/inflammatory processes the d

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Феномен тематичного парку як інноваційної моделі середовищних музеїв у ХХІ ст.

Проаналізовано феномен тематичного парку як інноваційної моделі середовищних музеїв.Застосовано культурологічний підхід з використанням методів аналізу та  синтезу.Розглянуто тематични

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Impact of changing treatment strategy based on circulating tumor cells on postoperative survival of breast cancer

BackgroundWe sought to explore the impact of changing treatment strategy based on circulating tumor cells (CTC) on postoperative survival of breast cancer.MethodsWe retrospectively analyzed records of patients who underwent surgery for early-stage breast cancer at Beijing Friendship Hospital from January 2016 to January 2018 and regularly underwent

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Landscape of Coronal X-Ray Variability and Cycles

Coronal (1–10 MK) X-rays display dramatic variability over the Sun’s iconic 11 yr magnetic dynamo cycle: already a factor of 4 in the soft 0.1–2.4 keV “ROSAT band,” soaring to more dorisvale station for sale than 100 at harder energies (>10 keV).The high-energy variations impact heliospheric space weather (SW); presumably likewise for hos

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